Linear models of activation cascades: analytical solutions and coarse-graining of delayed signal transduction
نویسندگان
چکیده
منابع مشابه
Linear models of activation cascades: analytical solutions and coarse-graining of delayed signal transduction
Cellular signal transduction usually involves activation cascades, the sequential activation of a series of proteins following the reception of an input signal. Here, we study the classic model of weakly activated cascades and obtain analytical solutions for a variety of inputs. We show that in the special but important case of optimal gain cascades (i.e. when the deactivation rates are identic...
متن کاملCoarse graining in spin foam models
We formulate the problem of finding the low-energy limit of spin foam models as a coarse-graining problem in the sense of statistical physics. This suggests that renormalization group methods may be used to find that limit. However, since spin foams are models of spacetime at Planck scale, novel issues arise: these microscopic models are sums over irregular, backgroundindependent lattices. We s...
متن کاملCoarse graining
Multiscale simulations For nearly all systems of interest to us, the most transferrable and fundamental description of matter is one that invokes quantum mechanics. At the highest level of accuracy, this amounts to solving Schrodinger’s equation for all of the subatomic particles in a system. Computationally, many approximations need to be made in order to use ab initio methods, and even these ...
متن کاملon the effect of linear & non-linear texts on students comprehension and recalling
چکیده ندارد.
15 صفحه اولMAPK Cascades in Guard Cell Signal Transduction
Guard cells form stomata on the epidermis and continuously respond to endogenous and environmental stimuli to fine-tune the gas exchange and transpirational water loss, processes which involve mitogen-activated protein kinase (MAPK) cascades. MAPKs form three-tiered kinase cascades with MAPK kinases and MAPK kinase kinases, by which signals are transduced to the target proteins. MAPK cascade ge...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of The Royal Society Interface
سال: 2016
ISSN: 1742-5689,1742-5662
DOI: 10.1098/rsif.2016.0409